Research Paper Volume 11, Issue 2 pp 590—614

Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism

Figure 4. Macaque P3 BMSCs stained with senescence-associated SA-β-gal (A) and (B) show young macaque and aged macaque P3 BMSCs, respectively (×100). The results showed that the percentage of positive BMSC staining in the young group was 1.33 ± 1.51%, which was significantly lower than that in the aged group (35.33 ± 3.88%, p<0.01), suggesting that the BMSCs in aged macaques exhibit cell senescence earlier than those in young macaques.