Research Paper Volume 11, Issue 5 pp 1389—1403

SP1-induced lncRNA TINCR overexpression contributes to colorectal cancer progression by sponging miR-7-5p

Figure 3. TINCR knockdown suppressed CRC cells proliferation, migration and invasion. (A) The relative expression of TINCR were detected after transfecting with siTINCR#1, siTINCR#2 or negative control (si-NC) in HCT116 and HCT8 cells. (B, C) Cells proliferation were evaluated in TINCR knockdown CRC cells using CCK-8 (B) and colony formation (C). (D, E) Wound healing (D) and transwell invasion (E) assays were performed to assess the ability of TINCR knockdown CRC cells. Data were shown as mean±S.D.. *P<0.05, **P<0.01. ***P<0.001.