Research Paper Volume 11, Issue 5 pp 1389—1403

SP1-induced lncRNA TINCR overexpression contributes to colorectal cancer progression by sponging miR-7-5p

Figure 6. miR-7-5p inhibition could reverse the inhibitory effect of TINCR downregulation. (A) miR-7-5p was downregulated in TINCR knockdown CRC cells. (B, C, D) The cell proliferation, migration and invasion were assessed using CCK-8 (B), Wound-healing (C) and transwell invasion (D) assays in cells cotransfected with siTINCR#1 and antagomiR-7-5p or antagomiR-NC. The data are shown as the mean±S.D. of three independent experiments. *P<0.05, **P<0.01. ***P<0.001.