Research Paper Volume 11, Issue 6 pp 1832—1849

White light emitting diode induces autophagy in hippocampal neuron cells through GSK-3-mediated GR and RORα pathways

Figure 5. White LED light influences the circadian rhythm of autophagy-related genes expression in HT-22 cells. (A) Lc3b mRNA, with no clear pattern of circadian rhythm and no significant alterations in Light group; (BC) Atg3 and atg5 mRNA, showing significantly blunted fluctuation in light-exposed cells; (D) Atg7 mRNA, showing a continuous increase in mRNA abundance until a plateau was reached 42 h after light exposure.