Research Paper Volume 11, Issue 10 pp 3156—3169

Age-related hearing loss accelerates cerebrospinal fluid tau levels and brain atrophy: a longitudinal study

Figure 2. The longitudinal influences of ARHL on CSF biomarkers. ARHL at baseline was not associated with the change rate of Aβ42 (A), but with the faster elevation rates of CSF tau (B) and ptau181 (C). All the above analyses were adjusted for age, gender, education, APOE4 status, pathological diagnosis of AD, DM2, hypertension, hyperlipidemia, BMI, and extracted CSF volume. *p value was calculated for the total sample.