Figure 5. The longitudinal influences of ARHL on structural measurements of entorhinal cortex. ARHL at baseline was associated with more rapid cortical thinning in bilateral entorhinal cortex in prodromal AD stage (A–D). All analyses were adjusted for age, gender, education, APOE4 status, pathological diagnosis of AD, DM2, hypertension, hyperlipidemia, BMI, and intracranial volume. *p value was calculated for the total sample.