Research Paper Volume 11, Issue 13 pp 4706—4719

Tea polyphenol protects against cisplatin-induced meiotic defects in porcine oocytes

Figure 2. Effects of TP on the spindle/chromosome defects in DDP-exposed porcine oocytes. (A) Representative images of spindle morphologies and chromosome alignment in control, DDP-exposed and TP-supplemented oocytes. Scale bar, 5 μm. (B) The rate of aberrant spindles was recorded in control, DDP-exposed and TP-supplemented oocytes. (C) The rate of misaligned chromosomes was recorded in control, DDP-exposed and TP-supplemented oocytes. Data in were presented as mean percentage (mean ± SEM) of at least three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001.