Research Paper Volume 11, Issue 14 pp 4943—4969

D-ribose is elevated in T1DM patients and can be involved in the onset of encephalopathy

Figure 4. Nissl staining of hippocampal neurons of rats treated with BTMP. Animal groups and treatment were as described in Figure 2 except that hippocampal slices were prepared and stained with cresyl violet (panel A). Numbers of necrotic neurons were counted under a microscope as described in the Materials and Methods (panel B). The number of those groups are control (n=10), BTMP (n=9), T1DM (n=10) and T1DM+BTMP (n=10). All values are expressed as the mean ± S.E.M. “*” compared to the control group. “#” represents the difference between the T1DM and T1DM+BTMP groups. All values are expressed as the mean ± S.E.M. **, P < 0.01; #, P < 0.05; ##, P < 0.01.