Research Paper Volume 11, Issue 15 pp 5593—5612

TGFβ1- miR-140-5p axis mediated up-regulation of Flap Endonuclease 1 promotes epithelial-mesenchymal transition in hepatocellular carcinoma

Figure 10. Model for the TGFβ1-miR-140-5p axis in which up-regulation of FEN1 promotes HCC cells invasion and migration via accelerating the EMT process. EMT, epithelial-mesenchymal transition.