Expression of Concern
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 11, Issue 15 pp 5744—5756
miR-627-3p inhibits osteosarcoma cell proliferation and metastasis by targeting PTN
Figure 3. MiR-627-3p inhibits osteosarcoma cell proliferation. (A, B) MTT assays showing cell proliferation after transfection with miR-627-3p mimic/inhibitor in HOS, MG63 and MG63/dox cells. Data are the mean ± SEM. ** P< 0.05 vs. control group. (C, D) Colony formation assays showing HOS and MG63 cell proliferation after transfection with miR-627-3p mimic/inhibitor. Data are the mean ± SEM. ** P< 0.05 vs. control group. (E, F) AV-PI assay showing cell apoptosis among HOS cells transfected with miR-627-3p mimic/inhibitor. (G–J) Western blot and real-time PCR analyses of Cyclin D1 expression in osteosarcoma cells transfected with miR-627-3p mimic/inhibitor. Data are the mean ± SEM. ** P< 0.05.