Review Volume 11, Issue 17 pp 7307—7327

Metabolic remodeling induced by mitokines in heart failure

Figure 3. Systematic metabolism regulated by cell non-autonomous effect. FGF21: fibroblast growth factor 21; GDF15: growth differentiation factor 15; GI: gastrointestinal; MDPs: mitochondria-derived peptides; UPRmt: mitochondrial unfolded protein response.