Research Paper Volume 11, Issue 20 pp 8777—8791

LncRNA MALAT1 shuttled by bone marrow-derived mesenchymal stem cells-secreted exosomes alleviates osteoporosis through mediating microRNA-34c/SATB2 axis

Figure 5. Characterization of the OVX mouse model. (A) Three-dimensional CT image of distal femur (1 mm). (BF) Quantitative data of BV/TV (B), Tb.N (C), Tb.Th (D), BMD (E) and Tb.Sp (F) in distal femoral of mice. (G) The MALAT1 and miR-34c expression as well as the mRNA expression of SATB2 in femoral tissues evaluated by RT-qPCR. (H) The protein expression of SATB2 in femoral tissues evaluated by Western blot analysis. * p < 0.05 vs. control mice. Data were expressed with mean ± standard deviation. In Panel BF, the unpaired t test was used for data analysis.