Research Paper Volume 11, Issue 17 pp 7294—7306

Impact of NF-κB pathway on the apoptosis-inflammation-autophagy crosstalk in human degenerative nucleus pulposus cells

Figure 1. The expression of TNF-α, IL-1β, P65 and cleaved caspase 3 in human NP tissues from LVF and DDD group. (A), (B), (C) and (D) Immunohistochemistry results show that the levels of TNF-α (A), IL-1β (B), P65 (C) and cleaved caspase-3 (D) were significantly increased in NP tissues from patients with DDD (magnification ×400); (E) Western blot for the protein level of TNF-α, IL-1β, P65 and cleaved caspase 3. Values are means ±SEM.*p<0.05 vs. LVF group.