Research Paper Volume 11, Issue 17 pp 7294—7306

Impact of NF-κB pathway on the apoptosis-inflammation-autophagy crosstalk in human degenerative nucleus pulposus cells

Figure 6. Inhibiting NF-κB promotes autophagy through AKT/mTOR pathway. (A) Western blot for the protein level of p-AKT, AKT, p-mTOR and mTOR. (B) After the addition of an AKT activator (SC79), Western blot for the protein level of p-AKT, AKT, p-mTOR, mTOR, LC3 and P62. Values are means ±SEM.*p<0.05 vs. control group, #p<0.05 vs. LPS group, ##p<0.05 vs. P65-siRNA+LPS group.