Research Paper Volume 11, Issue 20 pp 8892—8910

TGF-β receptor inhibitor LY2109761 enhances the radiosensitivity of gastric cancer by inactivating the TGF-β/SMAD4 signaling pathway

Figure 4. Effects of LY on the migration and invasion abilities of irradiation induced GC cell lines. (A) Cell migration assay: captured images of wound healing assay in GC cells influenced by LY with or without irradiation treatment, columns indicated the percentage of wound healing width in four groups. (B) Cell invasion assay: captured images of transwell assay in GC cells influenced by LY with or without irradiation treatment, columns indicated the invaded cell percentage in four groups. All data represent three independent experiments, mean ± SEM, *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001.