Research Paper Volume 11, Issue 21 pp 9264—9279

Dopaminergic neuron injury in Parkinson’s disease is mitigated by interfering lncRNA SNHG14 expression to regulate the miR-133b/ α-synuclein pathway

Figure 7. SNHG14/miR-133b regulated α-syn expression. MN9D cells were transfected with various vectors and treated with or without rotenone. (A) Relative expression of miR-133b was detected by qRT-PCR. (B) Level of α-syn protein was analyzed using western blotting. **P<0.01 compared with pcDNA; ##P<0.01 compared with pcDNA-SNHG14+pre-NC. (C) Relative expression of miR-133b was determined with qRT-PCR. (D) Level of α-syn protein was analyzed using western blotting. **P<0.01 compared with control; ##P<0.01 compared with Ro+si-control; &&P<0.01 compared with Ro+si-SNHG14+NC.