Figure 4.Effect of pterostilbene treatment combined with Compound C or EX527 on cardiac toxicity and oxidative stress in DOX-exposure mice hearts. (A) Representative images of the ultrastructural morphology of mitochondria from the left ventricular myocardium of experimental mice (magnification: upper panel 9900 ×, lower panel 20,500 ×). (B) ROS level, (C) SOD and (D) GPx activity in the myocardial tissues are showed. The results are expressed as the mean ± SEM. *P < 0.05 vs. the Sham group, #P < 0.05 vs. the DOX-treated group, $P < 0.05 vs. the DOX+PTS cotreated group.
