Research Paper Volume 11, Issue 24 pp 11865—11879

MicroRNA 27b promotes cardiac fibrosis by targeting the FBW7/Snail pathway

Figure 1. The miR-27b expression (AC) The miR-27b expression in PIA of infarcted heart at different time points (A) and 10 % serum-treated CFs of rats (B) or angiotensin II (AngII, 100 nM; C) at designated time points. (D) The miR-27b expression in CMs and CFs. Data were represented as mean ± SEM (n=4). (E) The miR-27b expression in plasma specimens of healthy participants (n=16) and cardiac fibrosis patients (n=19). *, p<0.05; **, p<0.01; ***, p<0.001.