Research Paper Volume 11, Issue 24 pp 11937—11954

Hsa_circ_0006948 enhances cancer progression and epithelial-mesenchymal transition through the miR-490-3p/HMGA2 axis in esophageal squamous cell carcinoma

Figure 2. The hsa_circ_0006948 was up-regulated in ESCC tissues and correlates with poor patients prognosis. (A) hsa_circ_0006948 expression was assessed in cancer tissues and normal tissues. (B) The relative hsa_circ_0006948 expression was assessed in 153 ESCC patients. Blue: low level: Red: high level. (C) Present the ROC curve analysis of hsa_circ_0006948 for the diagnosis of ESCC. (D) The expression of hsa_circ_0006948 was significantly higher in patients with lymph nodes at N1-N3 stage than in those with lymph nodes at NO stage. (E) Kaplan-Meier’s analyses of correlations between the hsa_circ_0006948 expression levels and OS (overall survival) of 153 ESCC patients. (F) Present the ROC curve analysis of hsa_circ_0006948 for the prognosis of ESCC.