Figure 4. Univariate survival analysis of the hub genes was performed using the Kaplan-Meier curve. The 8 genes of 10 hub genes showed significant difference in OS. Each elevated expression in the 5 significant hub genes showed obviously significant worse OS in ccRCC samples, whereas elevation of the remaining 3 hub genes showed better OS (Logrank P < .05). Abbreviation: OS: overall survival; ccRCC: Clear cell renal cell carcinoma.