Figure 2. GPX1 is overexpressed and positively associated with higher tumor stage in ccRCC samples. (A) The mRNA expression levels of GPX1 were up-regulated in ccRCC samples, which were downloaded from TCGA-KIRC database containing 72 normal samples and 533 ccRCC samples. (B–C) The mRNA expression levels of GPX1 were up-regulated in ccRCC in statistics by Gumz et al. and Yusenko et al, which were downloaded from ONCOMINE database. The expression levels of GPX1 mRNA were compared in various clinical pathological parameters: (D) Gender, (E) M stage, (F) N stage, (G) T stage, (H) G stage, (I) TNM stage. (T means Territory; M means distant metastasis; N means Lymph node metastasis. ****, P < 0.0001, ***, P < 0.001, **, P < 0.01, NS means no significance, compared with the respective control).