Research Paper Volume 12, Issue 2 pp 1563—1576

SENP1 is a crucial promotor for hepatocellular carcinoma through deSUMOylation of UBE2T

Figure 1. SENP1 is overexpressed in HCC tissues. (A) The protein levels of SENP1 in adjacent normal tissues and tumor tissues were examined by Western blot. (B) The average relative protein levels of SENP1 in adjacent normal tissues and tumor tissues obtained from gray analysis of Western blot results. (C) The expression of SENP1 in adjacent normal tissues and tumor tissues was determined by immunohistochemical staining. (D) Kaplan-Meier’s analysis of the correlation between SENP1 levels and overall survival in HCC patients. (E, F) SENP1 expression in TCGA RNAseq database. (G) The association between SENP1 expression and survival rate in TCGA database. The representative images were selected from at least three independent experiments.