Research Paper Volume 12, Issue 3 pp 2595—2609

Notch1/2/3/4 are prognostic biomarker and correlated with immune infiltrates in gastric cancer

Figure 4. Notch genes expression and mutation analysis in GC. (A) Notch1, Notch2, Notch3 and Notch4 mutation rates were 14%, 13%, 9% and 11%, respectively. (B) Network for 4 Notch receptors and the 50 most frequently altered neighbor genes. (C) Genetic alterations in Notch receptor were correlated with longer DFS in gastric adenocarcinoma patients. (D) The relationship between genetic alterations in Notch and OS/DFS. Logrank test was used in analysis of OS/DFS.