Research Paper Volume 12, Issue 4 pp 3312—3339

Analysis of immune-related signatures of lung adenocarcinoma identified two distinct subtypes: implications for immune checkpoint blockade therapy

class="figure-viewer-img"

Figure 1. Identification of high-risk and low-risk subtypes of LUAD in TCGA cohort by consensus clustering. (A) The relationship between cophenetic, dispersion and silhouette coefficients with respect to number of clusters. (B) Kaplan-Meier survival plot of the high-risk versus the low-risk subtype. (C) Forest plot representation of multivariate Cox model depicted association between overall survival and LUAD subtypes with other clinical factors taken into account.