Research Paper Volume 12, Issue 6 pp 5244—5258

Increased expression of the mitochondrial derived peptide, MOTS-c, in skeletal muscle of healthy aging men is associated with myofiber composition

Figure 5. MOTS-c muscle protein or small mRNA expression does not correlate well with antioxidant-response element (ARE) related genes. Correlation between MOTS-c protein (AD) or small mRNA (EH) expression and mRNA levels of NFE2L2, HMOX1, NQO1 and SOD2 in muscle samples from young, middle-aged and older men. Significance was determined using linear regression for n=78 (protein correlations) or n=52 (MOTS-c mRNA correlations).