Research Paper Volume 12, Issue 7 pp 6030—6036

Elevated p38MAPK activity promotes neural stem cell aging

Figure 1. Increased p38MAPK activity in SVZ neurogenic niche with aging. (A) Representative immunofluorescence for P-p38MAPK in SVZ of young (2 month-old) and aged (over 24 month-old) C57BL/6J mice (n≥2). (B) Quantification of number of P-p38MAPK positive cells in this region. (C) MAPK11, MAPK12, MAPK13 and MAPK14 mRNA levels in SVZ of young (2 month-old) and aged (over 24 month-old) C57BL/6J mice (n≥4).