LncRNA Sox2OT-V7 promotes doxorubicin-induced autophagy and chemoresistance in osteosarcoma via tumor-suppressive miR-142/miR-22

Kewei Zhu; Yang Yuan; Jie Wen; Ding Chen; Weihong Zhu; Zhengxiao Ouyang; Wanchun Wang

doi:doi:10.18632/aging.103004

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Research Paper Volume 12, Issue 8 pp 6644—6666

LncRNA Sox2OT-V7 promotes doxorubicin-induced autophagy and chemoresistance in osteosarcoma via tumor-suppressive miR-142/miR-22

Figure 10. A mechanistic schematic diagram showing the Sox2OT-V7/miR-142/miR-22 axis modulating the autophagy in OS cells via the autophagy-related genes, ULK1, ATG4A, and ATG5.