Research Paper Volume 12, Issue 7 pp 6067—6088

Identification of an exosomal long non-coding RNAs panel for predicting recurrence risk in patients with colorectal cancer

Figure 6. Evaluation of the 5-exolncRNAs panel in the test set. (A) Risk scores of 5-exolncRNAs were higher in CRC recurrence group than in nonrecurrence group; Data represents the median (interquartile range); [Mann–Whitney U test]. (B) ROC curve for discriminating CRC patients with recurrence from those without recurrence based on CEA, CA19-9 and 5-exolncRNAs panel. Sensitivity and specificity are reported. (C) Kaplan-Meier curves for RFS based on CEA, CA19-9 and 5-exolncRNAs panel; [log-rank test]. (D) Kaplan-Meier curves for OS based on CEA, CA19-9 and 5-exolncRNAs panel; [log-rank test]. (E and F) Multivariate Cox analysis for RFS (E) and OS (F) of CRC patients.