Research Paper Volume 12, Issue 7 pp 6401—6414

Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice

Figure 3. Spermidine and spermine attenuates oxidative stress in SAMP8. (A) The level of MDA in brain. (B) The level of ROS in the brain. Data represent mean ± SEM (n = 6 per group). #P < 0.05, ##P < 0.01, ###P < 0.001 vs. SAMR1; *P < 0.05, **P < 0.01, ***P < 0.001 vs. SAMP8.