Figure 8. Spermidine and spermine ameliorate inflammation in SAMP8. (A) The western blot of inflammatory protein. (B) The expression of NLRP3 in the brain. (C) The expression of IL-1β in the brain. (D) The expression of IL-18 in the brain. Data represent mean ± SEM (n = 3 per group). #P < 0.05, ##P < 0.01, ###P < 0.001 vs. SAMR1; *P < 0.05, **P < 0.01, ***P < 0.001 vs. SAMP8.