Research Paper Volume 12, Issue 8 pp 6756—6773

Exosomal miR-200c suppresses chemoresistance of docetaxel in tongue squamous cell carcinoma by suppressing TUBB3 and PPP2R1B

Figure 1. Docetaxel-resistant HSC-3 (HSC-3DR) cells exhibited increased cell viability and inhibited apoptosis. (A) Cell viability in response to different concentrations of DTX in tongue squamous cell carcinoma cell lines was determined by CCK8 assays. (B) Cell viability of HSC-3 and HSC-3DR cells in response to different concentrations of DTX was determined by CCK8 assays. (C) The morphology of HSC-3 and HSC-3DR cells (scale bars = 50 μm). (D) Apoptosis of HSC-3 and HSC-3DR cells was determined by flow cytometry. (E) Invasion ability of HSC-3 and HSC-3DR cells was determined by Transwell assays (scale bars = 50 μm). (F) Migration ability of HSC-3 and HSC-3DR cells was determined by Transwell assays (scale bars = 50 μm). Data are presented as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.