Research Paper Volume 12, Issue 8 pp 6756—6773

Exosomal miR-200c suppresses chemoresistance of docetaxel in tongue squamous cell carcinoma by suppressing TUBB3 and PPP2R1B

Figure 6. MiR-200c-carrying exosomes promoted apoptosis and inhibited migration ability in docetaxel-resistant HSC-3 (HSC-3DR) cells. (A) Apoptosis was determined by flow cytometry in HSC-3DR cells treated with miR-200c-carrying exosomes or miR-200c-carrying exosomes with the miR-200c inhibitor. (B) Invasion ability was determined by Transwell assays in HSC-3DR cells treated with miR-200c-carrying exosomes or miR-200c-carrying exosomes with the miR-200c inhibitor (scale bars = 50 μm). (C) Migration ability was determined by Transwell assays in HSC-3DR cells treated with miR-200c-carrying exosomes or miR-200c-carrying exosomes with the miR-200c inhibitor (scale bars = 50 μm). Data are presented as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.