Research Paper Volume 12, Issue 9 pp 7694—7703

Genetic variant of COL11A2 gene is functionally associated with developmental dysplasia of the hip in Chinese Han population

Figure 2. Relationship between the genotype of rs9277935 and COL11A2 expression in DDH joint tissues. (A) DDH Patients with genotype TT have a significantly increased expression of COL11A2 than those with GG (p = 0.02 for articular cartilage; p = 0.036 for joint ligament). (B) Immunofluorescent assay of COL11A2 (green) expression and nucleus (blue) in the cartilage and ligament tissues in DDH patients with different genotypes observed under confocal microscopy.