Research Paper Volume 12, Issue 7 pp 6456—6466

FGF22 promotes generation of ribbon synapses through downregulating MEF2D

Figure 2. FGF22 suppresses MEF2D in the cultured mouse hair cells. (A, B) Cultured hair cells were transduced with AAV-FGF22 or AAV-shFGF22 or control AAV-scr (scramble) and assessed for MEF2D levels by RT-qPCR (A), and by ELISA (B). (C, D) Cultured hair cells were transduced with AAV-MEF2D or AAV-shMEF2D or control AAV-scr (scramble) and assessed for FGF22 levels by RT-qPCR (C), and by ELISA (D). *p<0.05. N=5.