Research Paper Volume 12, Issue 8 pp 6891—6903

Hypoxia-induced let-7f-5p/TARBP2 feedback loop regulates osteosarcoma cell proliferation and invasion by inhibiting the Wnt signaling pathway

Figure 7. Schematic representation of the let-7f-5p/TARBP2 regulatory feedback loop in OS cells, which is induced by hypoxia and reduces the expression of let-7f-5p and TARBP2 in OS cells. A hypoxia-induced let-7f-5p/TARBP2 feedback loop regulates OS cell proliferation and invasion by inhibiting the Wnt signaling pathway.