Research Paper Volume 12, Issue 12 pp 11349—11363

Computational study on new natural compound inhibitors of indoleamine 2,3-dioxygenase 1

Figure 2. (A) ZINC000012495022-IDO complex. Schematic drawing of interactions between ligands and IDO, the surface of binding area were added, blue represented positive charge, red represented negative charge, and ligands were shown in sticks, the structure around the ligand-receptor junction were shown in thinner sticks. (B) ZINC000003791817-IDO complex. Schematic drawing of interactions between ligands and IDO, the surface of binding area were added, blue represented positive charge, red represented negative charge, and ligands were shown in sticks, the structure around the ligand-receptor junction were shown in thinner sticks. (C) Epacadostat-IDO complex. Schematic drawing of interactions between ligands and IDO, the surface of binding area were added, blue represented positive charge, red represented negative charge, and ligands were shown in sticks, the structure around the ligand-receptor junction were shown in thinner sticks.