LncRNA ILF3-AS1 mediated the occurrence of epilepsy through suppressing hippocampal miR-212 expression

Xiaodong Cai; Ling Long; Chao Zeng; Guanzhong Ni; Yangyang Meng; Qiang Guo; Ziyi Chen; Zhong Li

doi:doi:10.18632/aging.103148

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Research Paper Volume 12, Issue 9 pp 8413—8422

LncRNA ILF3-AS1 mediated the occurrence of epilepsy through suppressing hippocampal miR-212 expression

Figure 5. Ectopically expressed ILF3-AS1 targets miR-212. (A) Starbase (http://starbase.sysu.edu.cn/index.php) analysis predicting a binding site between ILF3-AS1 and miR-212. (B) qRT-PCR analysis of miR-212 expression. (C) ILF3-AS1-luciferase reporter assay showing miR-212 overexpression decreases ILF3-AS1 expression in astrocytes. (D) Forced ILF3-AS1 expression suppresses miR-212 expression in astrocytes. **p<0.01.