Research Paper Volume 12, Issue 11 pp 10259—10274

Structural plasticity of the bilateral hippocampus in glioma patients

Figure 4. Alteration of the dALFF in high-grade glioma patients. (A) The left HGG group showed significantly increased temporal variability of the dALFF in the bilateral hippocampus compared to HCs using a two-sample t-test (FDR-corrected cluster level p < 0.05, cluster size > 10). (B, C) For left hemispheric high-grade glioma patients, a significant increase in the dALFF was observed in both the entire left and right hippocampi in the HGG group compared to HCs (one-way ANOVA with Bonferroni correction, * p < 0.05, *** p < 0.001). (D) The right HGG group showed significantly increased temporal variability of the dALFF in the bilateral hippocampus compared to HCs using a two-sample t-test (FDR-corrected cluster level p < 0.05, cluster size > 10). (E, F) For right hemispheric glioma, a significant increase in the dALFF was observed in both the entire left and right hippocampi in the HGG group compared to HCs (one-way ANOVA with Bonferroni correction, * p < 0.05, ** p < 0.01).