Research Paper Volume 12, Issue 11 pp 10275—10289

UBE2T promotes glioblastoma invasion and migration via stabilizing GRP78 and regulating EMT

Figure 1. Ubiquitin-conjugating enzyme E2T (UBE2T) is an independent risk factor for gliomas. (A) Overlapping differentially expressed genes of recurrent and primary glioblastoma (GBM) compared with the findings in normal brain tissues. (B) UBE2T expression in recurrent GBM and normal tissues from the Genotype-Tissue Expression Project (GTEx) and Chinese Glioma Genome Atlas (CGGA) databases. (C) UBE2T expression in primary GBM and normal tissues from the GTEx and CGGA databases. (D) Overall survival analysis according to UBE2T expression in glioma using the GEPIA tool. (E) Disease-free survival analysis according to UBE2T expression in glioma using the GEPIA tool. (F) Multivariate analysis of the relationship of UBE2T with overall survival in glioma using the CGGA RNA sequencing dataset.