Research Paper Volume 12, Issue 11 pp 10381—10397

High circ-SEC31A expression predicts unfavorable prognoses in non-small cell lung cancer by regulating the miR-520a-5p/GOT-2 axis

Figure 3. Downregulating circ-SEC31A suppressed NSCLC invasion and migration both in vitro and in vivo. (A, B) Cell migration (A) and invasion (B) were assessed in both A549 and H1650 cells using Transwell assays. Data are presented as mean ± SD; ***P<0.001 vs. NC. (C) Live imaging showing the effects of hsa_circ_000142 on the metastasis of A549 cells 30 d after intravenous tail injection.