Research Paper Volume 12, Issue 11 pp 10427—10440

LncRNA PVT1 promotes exosome secretion through YKT6, RAB7, and VAMP3 in pancreatic cancer

Figure 3. PVT1 promotes the movement of MVBs towards the plasma membrane. (A) Analysis of CD63 (red) in PVT1-overexpressing HS766T cells, as determined by confocal microscope. Nuclei were labeled with DAPI (blue). (B) Analysis of YKT6 (green) and CD63 (red) in PVT1-overexpressing HS766T cells, as determined by confocal microscope. (C) Exosomes in PVT1-overexpressing HS766T cells, as determined by electron microscope.