Research Paper Volume 12, Issue 11 pp 10544—10555

Long noncoding RNA LINC00460 conduces to tumor growth and metastasis of hepatocellular carcinoma through miR-342-3p-dependent AGR2 up-regulation

Figure 6. Knockdown of LINC00460 suppresses HCC progression in vivo. (A, B) Pictures about tumor growth in the Lv-LINC00460 group and the control group was shown (C). Corresponding tumor growth curve. (D) The level of miR-342-3p was detected through qRT-PCR. (E, F) The expression of AGR2 was detected through western blot and data statistics was also shown. (GH) Immunohistochemical (IHC) was conducted to examine the expression of Ki67 and VEGF in tissues. *P < 0.05, **P < 0.01vs the control group.