Research Paper Volume 12, Issue 11 pp 10556—10577

T1-11, an adenosine derivative, ameliorates aging-related behavioral physiology and senescence markers in aging mice

Figure 3. The effect of T1-11 on oxidant/antioxidant stress parameters in the serum, cortex, and hippocampus of D-gal-induced aging mice. After treament, serum, cortex, and hippocampus tissue of were collected. The level of MDA (A) and the activity of CAT (B), SOD (C), and GSH-Px (D) in the serum, cortex, and hippocampus of D-gal-induced aging mice were detected. Data are mean ± SD (n = 6). Significant difference between control and D-gal-induced aging mice is indicated by * p < 0.05, ** p < 0.01 compared with the control group. Significant difference between the mice treated with D-gal alone and the mice treated with D-gal combined with Vit.E or T1-11 is indicated by #p < 0.05, ##p < 0.01 compared with D-gal group.