Research Paper Volume 12, Issue 11 pp 11004—11024

Upregulation of Mlxipl induced by cJun in the spinal dorsal horn after peripheral nerve injury counteracts mechanical allodynia by inhibiting neuroinflammation

Figure 7. Upregulation of Mlxipl induced by cJun in the spinal dorsal horn after peripheral nerve injury counteracts mechanical allodynia by inhibiting neuroinflammation. CJun expression in the SDH was upregulated after peripheral nerve injury, and this increased Mlxipl transcription. Upregulation of Mlxipl counteracts mechanical allodynia by inhibiting neuroinflammation derived from microglia in the SDH.