Research Paper Volume 12, Issue 12 pp 12119—12141

Serum proteomic predicts effectiveness and reveals potential biomarkers for complications in liver transplant patients

Figure 2. Serum proteomic profiling analysis for perioperative group, healthy controls (blue), paired post-transplant patients (green) and pre-transplant patients (red). (A) Representative mass spectra of three samples in healthy controls, post-transplant patients and pre-transplant patients in the mass range from 1000 to 10,000 Da. (B) Overall sum of the spectra in the mass range from 1000 to 10,000 Da obtained from perioperative group described above. (C) Bivariate plot of perioperative group with the most differentiated two peaks (m/z: 2216, 1950). (D) 3D plot of perioperative group. (E, G, I) Comparison of the spectra of three peaks in healthy controls, post-transplant patients and pre-transplant patients. (F, H, J) ROC curves for three selected peaks with their AUC values. (K) Average expression levels of three selected peaks in healthy controls, post-transplant patients and pre-transplant patients and their respective p-values. Values are expressed as mean ± SD. (***p < 0.001, **p < 0.01, *p < 0.05).