COVID-19 Research Paper Volume 12, Issue 12 pp 11263—11276

De novo design of protein peptides to block association of the SARS-CoV-2 spike protein with human ACE2

Figure 4. Sequence logo analysis of the evolution-based design results. Four sets of profile energy weight were used: 0.25 (A), 0.50 (B), 0.75 (C) and 1.00 (D).