Expression of Concern
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This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 12, Issue 14 pp 14157—14173
Circular RNA hsa_circ_0000073 contributes to osteosarcoma cell proliferation, migration, invasion and methotrexate resistance by sponging miR-145-5p and miR-151-3p and upregulating NRAS
Figure 7. Knockdown of hsa_circ_0000073 prevented tumor growth of OS by regulating NRAS in vivo. (A) Collected tumors were exhibited after hsa_circ_0000073 knockdown. (B) After hsa_circ_0000073 knockdown, NRAS expression was assessed using IHC and western blot assays. Magnification, ×100; Scale bar=100 μm. (C) qRT-PCR analyses of hsa_circ_0000073, miR-145-5p and miR-151-3p. (D) A skeleton diagram is displayed. *P<0.05.