Research Paper Volume 12, Issue 14 pp 14189—14204

Co-exposure to multi-walled carbon nanotube and lead ions aggravates hepatotoxicity of nonalcoholic fatty liver via inhibiting AMPK/PPARγ pathway

Figure 1. NAFLD models were successfully established in mice. (A) The body weight change curve of mice in the normal diet and high-fat diet groups (*P<0.05, compared to normal diet mice). (B) The weight of mice organs including the liver, heart, lung, spleen and kidney in the normal diet and high-fat diet groups (*P<0.05, compared to normal diet mice). (C) The serum levels of lipoproteins (CHOL, TG, HDL and LDL) of mice in the normal diet and high-fat diet groups (*P<0.05 and **P<0.01, compared to normal diet mice). (D) The serum levels of hepatic damage biomarkers (ALT, AST and ALP) in the normal diet and high-fat diet groups.