Research Paper Volume 12, Issue 14 pp 14189—14204

Co-exposure to multi-walled carbon nanotube and lead ions aggravates hepatotoxicity of nonalcoholic fatty liver via inhibiting AMPK/PPARγ pathway

Figure 5. MWCNTs and PbAc exposure significantly aggravated the hepatic fibrosis and steatosis in NAFLD mice. (A) Upon the low dose of PbAc, MWCNTs or MWCNTs + PbAc administration, Masson staining was conducted to detect the collagen deposition (blue indicates collagen) in liver tissues of control and NAFLD mice. (B) Oil red O staining was performed to detect the lipidoses (red indicates lipid) in liver tissues of control and NAFLD mice.