Research Paper Volume 12, Issue 14 pp 14189—14204

Co-exposure to multi-walled carbon nanotube and lead ions aggravates hepatotoxicity of nonalcoholic fatty liver via inhibiting AMPK/PPARγ pathway

Figure 6. MWCNTs and PbAc exposure significantly induced apoptosis in primary hepatocytes isolated from NAFLD mice. (A) After treatment with the low dose of PbAc, MWCNTs or MWCNTs + PbAc, apoptotic analyses were performed in primary hepatocytes from control and NAFLD mice using a flow cytometry. (B, C) Apoptotic rates in primary hepatocytes from control and NAFLD mice were statistically analyzed (***P<0.001, compared to saline water).